Angiotensin-converting enzyme 2 protects from severe acute lung failure
Identifieur interne : 004C74 ( Main/Exploration ); précédent : 004C73; suivant : 004C75Angiotensin-converting enzyme 2 protects from severe acute lung failure
Auteurs : Yumiko Imai [Autriche] ; Keiji Kuba [Autriche] ; Shuan Rao [République populaire de Chine] ; Yi Huan [République populaire de Chine] ; Feng Guo [République populaire de Chine] ; Bin Guan [République populaire de Chine] ; Peng Yang [République populaire de Chine] ; Renu Sarao [Autriche] ; Teiji Wada [Autriche] ; Howard Leong-Poi [Canada] ; Michael A. Crackower [Canada] ; Akiyoshi Fukamizu [Japon] ; Chi-Chung Hui [Canada] ; Lutz Hein [Allemagne] ; Stefan Uhlig [Allemagne] ; Arthur S. Slutsky [Canada] ; Chengyu Jiang [République populaire de Chine] ; Josef M. Penninger [Autriche]Source :
- Nature [ 0028-0836 ] ; 2005-07-07.
Descripteurs français
- KwdFr :
- Acides (pharmacologie), Analyse de variance, Angiotensine-II (métabolisme), Animaux, Carboxypeptidases (déficit), Carboxypeptidases (génétique), Carboxypeptidases (métabolisme), Délétion de gène, Humains, Maladie aigüe, Maladies pulmonaires (anatomopathologie), Maladies pulmonaires (enzymologie), Maladies pulmonaires (génétique), Maladies pulmonaires (physiopathologie), Modèles animaux de maladie humaine, Oedème pulmonaire (anatomopathologie), Oedème pulmonaire (physiopathologie), Oxygène (sang), Peptidyl-Dipeptidase A, Perméabilité capillaire, Poumon (anatomopathologie), Poumon (physiopathologie), Récepteur de type 1 à l'angiotensine-II (métabolisme), Récepteur de type 2 à l'angiotensine-II (métabolisme), Sepsie (anatomopathologie), Sepsie (enzymologie), Sepsie (génétique), Souris, Souris knockout, Souris transgéniques, Syndrome de détresse respiratoire de l'adulte (anatomopathologie), Syndrome de détresse respiratoire de l'adulte (enzymologie), Syndrome de détresse respiratoire de l'adulte (génétique), Transgènes (génétique).
- MESH :
- anatomopathologie : Maladies pulmonaires, Oedème pulmonaire, Poumon, Sepsie, Syndrome de détresse respiratoire de l'adulte.
- déficit : Carboxypeptidases.
- enzymologie : Maladies pulmonaires, Sepsie, Syndrome de détresse respiratoire de l'adulte.
- génétique : Carboxypeptidases, Maladies pulmonaires, Sepsie, Syndrome de détresse respiratoire de l'adulte, Transgènes.
- métabolisme : Angiotensine-II, Carboxypeptidases, Récepteur de type 1 à l'angiotensine-II, Récepteur de type 2 à l'angiotensine-II.
- pharmacologie : Acides.
- physiopathologie : Maladies pulmonaires, Oedème pulmonaire, Poumon.
- sang : Oxygène.
- Analyse de variance, Animaux, Délétion de gène, Humains, Maladie aigüe, Modèles animaux de maladie humaine, Peptidyl-Dipeptidase A, Perméabilité capillaire, Souris, Souris knockout, Souris transgéniques.
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- ACE inhibitor, Acids (pharmacology), Acute Disease, Analysis of Variance, Angiotensin II (metabolism), Animal, Animals, Capillary Permeability, Carboxypeptidases (deficiency), Carboxypeptidases (genetics), Carboxypeptidases (metabolism), Chemotherapy, Disease Models, Animal, Etiology, Gene Deletion, Human, Humans, Lung (pathology), Lung (physiopathology), Lung Diseases (enzymology), Lung Diseases (genetics), Lung Diseases (pathology), Lung Diseases (physiopathology), Mice, Mice, Knockout, Mice, Transgenic, Mouse, Oxygen (blood), Peptidyl-Dipeptidase A, Peptidyl-dipeptidase A, Pulmonary Edema (pathology), Pulmonary Edema (physiopathology), Receptor, Angiotensin, Type 1 (metabolism), Receptor, Angiotensin, Type 2 (metabolism), Recombinant protein, Respiratory Distress Syndrome, Adult (enzymology), Respiratory Distress Syndrome, Adult (genetics), Respiratory Distress Syndrome, Adult (pathology), Respiratory distress, Sepsis (enzymology), Sepsis (genetics), Sepsis (pathology), Severe acute respiratory syndrome, Transgenes (genetics).
- MESH :
- chemical , blood : Oxygen.
- chemical , deficiency : Carboxypeptidases.
- chemical , genetics : Carboxypeptidases.
- chemical , metabolism : Angiotensin II, Carboxypeptidases, Receptor, Angiotensin, Type 1, Receptor, Angiotensin, Type 2.
- chemical , pharmacology : Acids.
- enzymology : Lung Diseases, Respiratory Distress Syndrome, Adult, Sepsis.
- genetics : Lung Diseases, Respiratory Distress Syndrome, Adult, Sepsis, Transgenes.
- pathology : Lung, Lung Diseases, Pulmonary Edema, Respiratory Distress Syndrome, Adult, Sepsis.
- physiopathology : Lung, Lung Diseases, Pulmonary Edema.
- Acute Disease, Analysis of Variance, Animals, Capillary Permeability, Disease Models, Animal, Gene Deletion, Humans, Mice, Mice, Knockout, Mice, Transgenic, Peptidyl-Dipeptidase A.
Url:
- https://api.istex.fr/ark:/67375/GT4-694BDZK4-2/fulltext.pdf
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094998
DOI: 10.1038/nature03712
Affiliations:
- Allemagne, Autriche, Canada, Japon, République populaire de Chine
- Bade-Wurtemberg, District de Fribourg-en-Brisgau, Ontario, Vienne (Autriche)
- Fribourg-en-Brisgau, Pékin, Toronto, Vienne (Autriche)
- Université de Toronto
Links toward previous steps (curation, corpus...)
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Le document en format XML
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last="Wada">Teiji Wada</name><affiliation wicri:level="1"><country xml:lang="fr">Autriche</country><wicri:regionArea>IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna A-1030</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Leong Poi, Howard" sort="Leong Poi, Howard" uniqKey="Leong Poi H" first="Howard" last="Leong-Poi">Howard Leong-Poi</name><affiliation wicri:level="1"><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Cardiology, St. Michael's Hospital, Toronto, Ontario M5B 1W8</wicri:regionArea><wicri:noRegion>Ontario M5B 1W8</wicri:noRegion></affiliation></author><author><name sortKey="Crackower, Michael A" sort="Crackower, Michael A" uniqKey="Crackower M" first="Michael A." last="Crackower">Michael A. Crackower</name><affiliation wicri:level="1"><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Merck Frosst Centre for Therapeutic Research, Montreal, Quebec H3R 4P8</wicri:regionArea><wicri:noRegion>Quebec H3R 4P8</wicri:noRegion></affiliation></author><author><name sortKey="Fukamizu, Akiyoshi" sort="Fukamizu, Akiyoshi" uniqKey="Fukamizu A" first="Akiyoshi" last="Fukamizu">Akiyoshi Fukamizu</name><affiliation wicri:level="1"><country xml:lang="fr">Japon</country><wicri:regionArea>Center for Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba 305-8577</wicri:regionArea><wicri:noRegion>Tsukuba 305-8577</wicri:noRegion></affiliation></author><author><name sortKey="Hui, Chi Chung" sort="Hui, Chi Chung" uniqKey="Hui C" first="Chi-Chung" last="Hui">Chi-Chung Hui</name><affiliation wicri:level="4"><country xml:lang="fr">Canada</country><wicri:regionArea>Program in Developmental Biology, The Hospital for Sick Children and Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario MG5 1X8</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Hein, Lutz" sort="Hein, Lutz" uniqKey="Hein L" first="Lutz" last="Hein">Lutz Hein</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pharmacology, University of Freiburg, Freiburg 79104</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Fribourg-en-Brisgau</region><settlement type="city">Fribourg-en-Brisgau</settlement></placeName></affiliation></author><author><name sortKey="Uhlig, Stefan" sort="Uhlig, Stefan" uniqKey="Uhlig S" first="Stefan" last="Uhlig">Stefan Uhlig</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Pulmonary Pharmacology, Research Center Borstel, Borstel 23845</wicri:regionArea><wicri:noRegion>23845</wicri:noRegion><wicri:noRegion>Borstel 23845</wicri:noRegion></affiliation></author><author><name sortKey="Slutsky, Arthur S" sort="Slutsky, Arthur S" uniqKey="Slutsky A" first="Arthur S." last="Slutsky">Arthur S. Slutsky</name><affiliation wicri:level="4"><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Medicine and Interdepartmental Division of Critical Care, University of Toronto, St. Michael's Hospital, Toronto, Ontario M5B 1W8</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Jiang, Chengyu" sort="Jiang, Chengyu" uniqKey="Jiang C" first="Chengyu" last="Jiang">Chengyu Jiang</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Penninger, Josef M" sort="Penninger, Josef M" uniqKey="Penninger J" first="Josef M." last="Penninger">Josef M. 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type="ISSN">0028-0836</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0028-0836</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>ACE inhibitor</term><term>Acids (pharmacology)</term><term>Acute Disease</term><term>Analysis of Variance</term><term>Angiotensin II (metabolism)</term><term>Animal</term><term>Animals</term><term>Capillary Permeability</term><term>Carboxypeptidases (deficiency)</term><term>Carboxypeptidases (genetics)</term><term>Carboxypeptidases (metabolism)</term><term>Chemotherapy</term><term>Disease Models, Animal</term><term>Etiology</term><term>Gene Deletion</term><term>Human</term><term>Humans</term><term>Lung (pathology)</term><term>Lung (physiopathology)</term><term>Lung Diseases (enzymology)</term><term>Lung Diseases (genetics)</term><term>Lung Diseases (pathology)</term><term>Lung Diseases (physiopathology)</term><term>Mice</term><term>Mice, Knockout</term><term>Mice, Transgenic</term><term>Mouse</term><term>Oxygen (blood)</term><term>Peptidyl-Dipeptidase A</term><term>Peptidyl-dipeptidase A</term><term>Pulmonary Edema (pathology)</term><term>Pulmonary Edema (physiopathology)</term><term>Receptor, Angiotensin, Type 1 (metabolism)</term><term>Receptor, Angiotensin, Type 2 (metabolism)</term><term>Recombinant protein</term><term>Respiratory Distress Syndrome, Adult (enzymology)</term><term>Respiratory Distress Syndrome, Adult (genetics)</term><term>Respiratory Distress Syndrome, Adult (pathology)</term><term>Respiratory distress</term><term>Sepsis (enzymology)</term><term>Sepsis (genetics)</term><term>Sepsis (pathology)</term><term>Severe acute respiratory syndrome</term><term>Transgenes (genetics)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Acides (pharmacologie)</term><term>Analyse de variance</term><term>Angiotensine-II (métabolisme)</term><term>Animaux</term><term>Carboxypeptidases (déficit)</term><term>Carboxypeptidases (génétique)</term><term>Carboxypeptidases (métabolisme)</term><term>Délétion de gène</term><term>Humains</term><term>Maladie aigüe</term><term>Maladies pulmonaires (anatomopathologie)</term><term>Maladies pulmonaires (enzymologie)</term><term>Maladies pulmonaires (génétique)</term><term>Maladies pulmonaires (physiopathologie)</term><term>Modèles animaux de maladie humaine</term><term>Oedème pulmonaire (anatomopathologie)</term><term>Oedème pulmonaire (physiopathologie)</term><term>Oxygène (sang)</term><term>Peptidyl-Dipeptidase A</term><term>Perméabilité capillaire</term><term>Poumon (anatomopathologie)</term><term>Poumon (physiopathologie)</term><term>Récepteur de type 1 à l'angiotensine-II (métabolisme)</term><term>Récepteur de type 2 à l'angiotensine-II (métabolisme)</term><term>Sepsie (anatomopathologie)</term><term>Sepsie (enzymologie)</term><term>Sepsie (génétique)</term><term>Souris</term><term>Souris knockout</term><term>Souris transgéniques</term><term>Syndrome de détresse respiratoire de l'adulte (anatomopathologie)</term><term>Syndrome de détresse respiratoire de l'adulte (enzymologie)</term><term>Syndrome de détresse respiratoire de l'adulte (génétique)</term><term>Transgènes (génétique)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Oxygen</term></keywords><keywords scheme="MESH" type="chemical" qualifier="deficiency" xml:lang="en"><term>Carboxypeptidases</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Carboxypeptidases</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Angiotensin II</term><term>Carboxypeptidases</term><term>Receptor, Angiotensin, Type 1</term><term>Receptor, Angiotensin, Type 2</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Acids</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Maladies 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l'adulte</term><term>Transgènes</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Angiotensine-II</term><term>Carboxypeptidases</term><term>Récepteur de type 1 à l'angiotensine-II</term><term>Récepteur de type 2 à l'angiotensine-II</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lung</term><term>Lung Diseases</term><term>Pulmonary Edema</term><term>Respiratory Distress Syndrome, Adult</term><term>Sepsis</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Acides</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Maladies pulmonaires</term><term>Oedème pulmonaire</term><term>Poumon</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Lung</term><term>Lung Diseases</term><term>Pulmonary Edema</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Oxygène</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Acute Disease</term><term>Analysis of Variance</term><term>Animals</term><term>Capillary Permeability</term><term>Disease Models, Animal</term><term>Gene Deletion</term><term>Humans</term><term>Mice</term><term>Mice, Knockout</term><term>Mice, Transgenic</term><term>Peptidyl-Dipeptidase A</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Analyse de variance</term><term>Animaux</term><term>Délétion de gène</term><term>Humains</term><term>Maladie aigüe</term><term>Modèles animaux de maladie humaine</term><term>Peptidyl-Dipeptidase A</term><term>Perméabilité capillaire</term><term>Souris</term><term>Souris knockout</term><term>Souris transgéniques</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>ACE2</term><term>Animal</term><term>Chimiothérapie</term><term>Détresse respiratoire</term><term>Etiologie</term><term>Homme</term><term>Inhibiteur angiotensin converting enzyme</term><term>Peptidyl-dipeptidase A</term><term>Protéine recombinante</term><term>Souris</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass></profileDesc></teiHeader></TEI><affiliations><list><country><li>Allemagne</li><li>Autriche</li><li>Canada</li><li>Japon</li><li>République populaire de Chine</li></country><region><li>Bade-Wurtemberg</li><li>District de Fribourg-en-Brisgau</li><li>Ontario</li><li>Vienne (Autriche)</li></region><settlement><li>Fribourg-en-Brisgau</li><li>Pékin</li><li>Toronto</li><li>Vienne (Autriche)</li></settlement><orgName><li>Université de Toronto</li></orgName></list><tree><country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="Imai, Yumiko" sort="Imai, Yumiko" uniqKey="Imai Y" first="Yumiko" last="Imai">Yumiko Imai</name></region><name sortKey="Kuba, Keiji" sort="Kuba, Keiji" uniqKey="Kuba K" first="Keiji" last="Kuba">Keiji Kuba</name><name sortKey="Penninger, Josef M" sort="Penninger, Josef M" uniqKey="Penninger J" first="Josef M." last="Penninger">Josef M. Penninger</name><name sortKey="Penninger, Josef M" sort="Penninger, Josef M" uniqKey="Penninger J" first="Josef M." last="Penninger">Josef M. Penninger</name><name sortKey="Sarao, Renu" sort="Sarao, Renu" uniqKey="Sarao R" first="Renu" last="Sarao">Renu Sarao</name><name sortKey="Wada, Teiji" sort="Wada, Teiji" uniqKey="Wada T" first="Teiji" last="Wada">Teiji Wada</name></country><country name="République populaire de Chine"><noRegion><name sortKey="Rao, Shuan" sort="Rao, Shuan" uniqKey="Rao S" first="Shuan" last="Rao">Shuan Rao</name></noRegion><name sortKey="Guan, Bin" sort="Guan, Bin" uniqKey="Guan B" first="Bin" last="Guan">Bin Guan</name><name sortKey="Guo, Feng" sort="Guo, Feng" uniqKey="Guo F" first="Feng" last="Guo">Feng Guo</name><name sortKey="Huan, Yi" sort="Huan, Yi" uniqKey="Huan Y" first="Yi" last="Huan">Yi Huan</name><name sortKey="Jiang, Chengyu" sort="Jiang, Chengyu" uniqKey="Jiang C" first="Chengyu" last="Jiang">Chengyu Jiang</name><name sortKey="Yang, Peng" sort="Yang, Peng" uniqKey="Yang P" first="Peng" last="Yang">Peng Yang</name></country><country name="Canada"><noRegion><name sortKey="Leong Poi, Howard" sort="Leong Poi, Howard" uniqKey="Leong Poi H" first="Howard" last="Leong-Poi">Howard Leong-Poi</name></noRegion><name sortKey="Crackower, Michael A" sort="Crackower, Michael A" uniqKey="Crackower M" first="Michael A." last="Crackower">Michael A. Crackower</name><name sortKey="Hui, Chi Chung" sort="Hui, Chi Chung" uniqKey="Hui C" first="Chi-Chung" last="Hui">Chi-Chung Hui</name><name sortKey="Slutsky, Arthur S" sort="Slutsky, Arthur S" uniqKey="Slutsky A" first="Arthur S." last="Slutsky">Arthur S. Slutsky</name></country><country name="Japon"><noRegion><name sortKey="Fukamizu, Akiyoshi" sort="Fukamizu, Akiyoshi" uniqKey="Fukamizu A" first="Akiyoshi" last="Fukamizu">Akiyoshi Fukamizu</name></noRegion></country><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Hein, Lutz" sort="Hein, Lutz" uniqKey="Hein L" first="Lutz" last="Hein">Lutz Hein</name></region><name sortKey="Uhlig, Stefan" sort="Uhlig, Stefan" uniqKey="Uhlig S" first="Stefan" last="Uhlig">Stefan Uhlig</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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